About Bacmet

BacMet is an easy-to-use bioinformatics resource of antibacterial biocide- and metal-resistance genes. BacMet consists of two databases:

• A manually curated database of genes with experimentally confirmed resistance function
• A database of predicted resistance genes based on structural similarity to genes encoding proteins with experimentally confirmed function

BacMet provides a high quality, manually curated database of bacterial genes that are experimentally confirmed to confer resistance to metals and/or antibacterial biocides, fully referenced to the scientific literature. BacMet also includes a database of predicted resistance genes, as the resistance genes may differ between species and/or occur in different forms that are not (yet) experimentally investigated. The database of predicted genes is generated by structural similarity searches in public databases, using AlphaFold and FoldSeek.

The genes in the databases can be accessed through the browsing option, or theentire database can be downloaded for off-line analysis of larger datasets.